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Macmillan Higher Education Palgrave Higher Education

Advanced Organic Chemistry

Part B: Reaction and Synthesis

Edition 5th Edition
ISBN 9780387683546
Publication Date September 2007
Formats Paperback Ebook 
Publisher Springer

Since its original appearance in 1977, Advanced Organic Chemistry has maintained its place as the premier textbook in the field, offering broad coverage of the structure, reactivity and synthesis of organic compounds. As in the earlier editions, the text contains extensive references to both the primary and review literature and provides examples of data and reactions that illustrate and document the generalizations. While the text assumes completion of an introductory course in organic chemistry, it reviews the fundamental concepts for each topic that is discussed.

The two-part fifth edition has been substantially revised and reorganized for greater clarity. Among the changes: Updated material reflecting advances in the field since 2001’s Fourth Edition, especially in computational chemistry; A companion Web site provides digital models for study of structure, reaction and selectivity; Solutions to the exercises provided to instructors online.

The control of reactivity to achieve specific syntheses is one of the overarching goals of organic chemistry. Part B describes the most general and useful synthetic reactions, organized on the basis of reaction type. Together with Part A: Structure and Mechanisms, the two volumes are intended to provide the advanced undergraduate or beginning graduate student in chemistry with a sufficient foundation to comprehend and use the research literature in organic chemistry.

Francis A. Carey is a native of Pennsylvania, educated in the public schools of Philadelphia, at Drexel University (B.S. in chemistry, 1959), and at Penn State (Ph.D. 1963). Following postdoctoral work at Harvard and military service, he was appointed to the chemistry faculty of the University of Virginia in 1966. Prior to retiring in 2000, he regularly taught the two-semester lecture courses in general chemistry and organic chemistry. With his students, Professor Carey has published over forty research papers in synthetic and mechanistic organic chemistry.

Professor Sundberg is primarily engaged in teaching and chemical education. Along with Francis A. Carey he is the author of “Advanced Organic Chemistry. Professor Sundberg is also interested in synthetic methodology in heterocyclic chemistry and is the author of “Indoles” in the Best Synthetic Methods Series (Academic Press, 1996).

Alkylation of Enolates and Other Carbon Nucleophiles
Reactions of Carbon Nucleophiles with Carbonyl Compounds
Functional Group Interconversion by Substitution, Including Protection and Deprotection
Electrophilic Additions to Carbon-Carbon Multiple Bonds
Reduction of Carbon-Carbon Multiple Bonds, Carbonyl Groups, and Other Functional Groups
Concerted Cycloadditions, Unimolecular Rearrangements, and Thermal Eliminations
Organometallic Compounds of Group I and II Metals
Reactions Involving Transition Metals
Carbon-Carbon Bond-Forming Reactions of Compounds of Boron, Silicon, and Tin
Reactions Involving Carbocations, Carbenes, and Radicals as Reactive Intermediates
Aromatic Substitution Reactions
Multistep Syntheses.


From the reviews of the fifth edition: "Advanced Organic Chemistry … the well-known textbook for graduate students – has now appeared in a 5th edition. … Carey & Sundberg will be interesting to all students who seek a detailed understanding of organic chemistry, and who wish to refresh and embellish their existing knowledge. On the strength of the scope and quality of the explanations, this pair of texts is recommended for use as the resource of first resort for specific research questions in one’s later career." (www.organische-chemie.ch, January, 2008)
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